Programme de bourses "Echanges Universitaires"
Determinants of access to deworming in Lao PDR: a community-led intervention study in the province of Saravane
Abstract
Background
Food-borne trematodiasis (FBT) is one of the neglected tropical diseases (NTD) and a public health problem in Lao People’s Democratic Republic (Lao PDR). Approximately two and a half million Lao are infected with Opisthorchis viverrini. Many are co-infected with soil-transmitted helminth. Transmission of O. viverrini parasite occurs with eating of raw and insufficiently cooked infected fishes. Poor sanitation favour the transmission of the parasite to the intermediate snail and fish hosts. The study conducted in Saravane province documented that 50% of primary school children and 90% of adults are infected with O. viverrini. The risk factors for O. viverrini infection were highly prevalent: 75% of population reported eating raw and insufficiently cooked fish, only 1 out of 13 surveyed villages had latrine construction, and more than 80% of people did report not to know O. viverrini infection and its consequences on health. The drug treatment is efficacious. However, as long as the individual does not change the habit of raw food consumption the treatment must be repeated annually. This poses a terrible work load on the local health services which can not address.
Objectives
The following objectives are pursued: (1) to assess the status of helminth infection particularly Opisthorchis viverrini infection in selected communities in Saravane province; (2) to design and implement a community-led mass drug administration (MDA) intervention for the control of O. viverrini and STH in community; and (3) to evaluate community’s knowledge, attitude, and practice on MDA implemented by the communities.
Research activities performed
To the objective 1: A baseline survey was conducted in 10 out of 30 intervention villages in January and February 2010. Stool samples were examined, and interviews with head of households, in-depth interviews with villagers, key informant, drug distributors, and primary school children in two primary schools were performed.
To the objective 2: A one day training course for community leaders (village health volunteer, and head of village) from 30 villages was organized in March, and after the training the mass drug administration intervention in community was launched.
To the objective 3 – An evaluation of the community-led MDA activities was carried out in 10 of the 30 villages in March and April 2010 in which in-depth interviews of community leaders, key informants, and villagers were done in order to understand how people perceive regarding the MDA implementation.
Objectives and activities of next working period
In next months four objectives are pursued: (i) to analyze quantitatively and qualitatively the data collected over the last two years and to compile report and elaborate scientific publications, (ii) to finalize research publication which have been started in the last two years, (iii) to participate in formal courses at the University of Basel in order to enhance scientific skills and thinking in the field of specialization, and (iv) to develop the detailed research questions to be addressed in the year 2011 and to establish a working plan for all field work.
Funding
Regarding the study activities mentioned above, it was funded by TDR/WHO in Geneva, Switzerland. Further funding was granted by the Rudolf Geigy Foundation, Basel, Switzerland.
Contacts
PhD Fellow
Dr. med. Khampheng Phongluxa
National Institute of Public Health, Ministry of Health, Samsenthai Road, Ban Kaognot, Sisattanak District, Vientiane Capital, Lao PDR; Tel: +856-21-214 975 or +856-21-214 012 and Swiss Tropical and Public Health Institute, Department of Public Health and Epidemiology, P.O. Box, 4002 Basel, Switzerland, Tel.: +41 61 284-8614; E-mail: Khampheng.Phongluxa@unibas.ch
Supervisors
Dr. Peter Odermatt
Swiss Tropical and Public Health Institute, Department of Public Health and Epidemiology, P.O. Box, 4002 Basel, Switzerland, Tel.: +41 61 284-8214; Fax: +41 61 284-8105, E-mail: peter.odermatt@unibas.ch
Assoc. Professor Kongsap Akkhavong
Deputy Director, National Institute of Public Health, Ministry of Health, Samsenthai Road, Ban Kaognot, Sisattanak District, Vientiane Capital, Lao PDR; Tel: +856-21-214 975 or +856-21-214 012; Email: kongsap@hotmail.com

Figure 1: Field research team prepares activities (interviews, stool sample collection) in Dongkoneua village, Saravane district, Saravane province (11th January 2010).

Figure 2: Discussion with community leaders regarding the household selection, Saravane province (06th January 2010).

Figure 3: Stool sample analysis in the laboratory of the provincial hospital in Saravane

Figure 4: Opening ceremony of the one day training course on helminth infection and the conduction of mass drug administration with community leaders and village health volunteers, Saravane province (3rd to 5th March 2010)

Figure 5: Lesson regarding infection of helminth infections and control during the one day training course for community leaders held in Saravane district health office (3rd -5th March 2010)
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